蛋白名稱:KDR人重組蛋白，10012-H02H

蛋白構(gòu)建:A DNA sequence encoding the extracellular domain of human VEGFR2 (NP_002244.1) (Met 1-Glu 764) was fused with the Fc region of human IgG1 at the C-terminus.

表達(dá)宿主:HEK293 Cells

蛋白純度:> 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

蛋白活性:

1. Immobilized  Human VEGF121 (Cat:10008-HNAH) at 2 μg/mL (100 μL/well) can bind Human VEGFR2/KDR (ECD, hFc Tag)(Cat:10012-H02H), the EC50 of Human VEGFR2/KDR (ECD, hFc Tag)(Cat:10012-H02H) is 6-48 ng/mL.

2. Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC). The * for this effect is typically 20-120 ng/mL in the presence of 10 ng/mL recombinant human VEGF165.

蛋白內(nèi)毒素:< 1.0 EU per μg of the protein as determined by the LAL method

預(yù)測(cè)N端:Ala 20

蛋白分子量:The recombinant human VEGFR2/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 979 amino acids and predicts a molecular mass of 109 kDa. The apparent molecular mass of human VEGFR2/Fc monomer is approximatly 150-160 KDa in SDS-PAGE under reducing conditions due to glycosylation.

蛋白NP號(hào):NP_002244.1

蛋白氨基酸序列:Met1-Glu764

蛋白標(biāo)簽:C-human IgG1-Fc

歡迎去義翹神州網(wǎng)查看KDR人重組蛋白，10012-H02H詳細(xì)信息。網(wǎng)址：https://cn.sinobiological.com/recombinant-proteins/human-vegfr2-kdr-10012-h02h

義翹神州研發(fā)團(tuán)隊(duì)擁有多年的重組蛋白研發(fā)經(jīng)驗(yàn)。多年來，我們的團(tuán)隊(duì)已開發(fā)出超過9300余種重組蛋白，涵蓋免疫檢查點(diǎn)、抗體藥物靶點(diǎn)、CAR-T細(xì)胞治療靶點(diǎn)、Fc受體、流感病毒蛋白以及細(xì)胞因子等熱門研究領(lǐng)域。義翹神州重組蛋白具有高純度、高生物活性和低內(nèi)毒素水平等特性，可為生物藥靶點(diǎn)發(fā)現(xiàn)、蛋白質(zhì)結(jié)構(gòu)和功能分析、細(xì)胞療法和重組酶酶學(xué)性質(zhì)等科學(xué)研究提供支持。

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